Arsenal: The hosts are faced with the decision of whether to rest players ahead of their Europa League semi-final or use the game to prepare. Aaron Ramsey is available once against following a shin injury, but Jack Wilshere could sit the game out with an ankle problem. Henrikh Mkhitaryan will once again miss out due to a knee problem.
West Ham: Adrian could come in for Joe Hart in goal after David Moyes questioned the England international's form. James Collins will not feature as he continues his comeback from an ankle injury, whilstAngelo Ogbonna is a doubt with tendinitis in his knee. Winston Reid (knee), Michail Antonio (hamstring) and Sam Byram (ankle) all remain sidelined, but Pedro Obiang could make a shock return after initially been rules out for the season..
Arsenal boss Arsene Wenger on departing the club:
"After careful consideration and following discussions with the club, I feel it is the right time for me to step down at the end of the season.
"I am grateful for having had the privilege to serve the club for so many memorable years. I managed the club with full commitment and integrity.
"I want to thank the staff, the players, the directors and the fans who make this club so special. I urge our fans to stand behind the team to finish on a high."
West Ham boss David Moyes on Wenger:
"It's been an incredible achievement for him to be in the job that long - as it was for Sir Alex Ferguson. I thought I did well with 11 years at Everton.
"Real football people appreciate what he's done. He is a proper football man, he lives and breathes it, he's dedicated to his job and his sport.
"I'd probably wish it hadn't been announced before this weekend but most people appreciate Arsene and what he has done in football."
Did you know?
Arsenal have only lost one of their last 21 games against West Ham in all competitions (W16, D4, L1).
Form:
Possible lineups:
Arsenal: Cech; Bellerin, Mustafi, Koscielny, Monreal; Xhaka, Elneny, Ramsey; Ozil, Lacazette, Aubameyang.
West Ham: Hart; Rice, Ogbonna, Cresswell; Zabaleta, Kouyate, Noble, Masuaku; Mario, Lanzini; Arnautovic.